Dr. B's Cannabis Corner #21: CBD Revisited
Last week I had the privilege of attending an online lecture from Ethan Russo, one of the big names in scientific cannabis research. This is the guy who published about the “entourage effect” in his groundbreaking article, Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects, in 2011. (This is one of the articles that inspired me to create EWC’s famous Understanding Medical Cannabis charts).
Then a few days later, while I was out and about, I saw a poster advertising an event: “American CBD Expo,” February 9-11, 2019, in our very own San Jose.
2. CBD is sedating
3. A little CBD is enough
4. CBD is the same from hemp, medical cannabis, or concentrates
We all know that CBD works better when combined with other cannabinoids, especially THC. Hemp and most concentrates have little to no THC and other cannabinoids or terpenoids. And do not forget many manufactured CBD products are mislabeled and misleading.
5. CBD works by activating cannabinoid receptors
CBD actually decreases CB1 and CB2 activity levels. For example, CBD causes a mild to moderate decrease in the effects of THC at the CB1 receptor. On the other hand, CBD can indirectly stimulate cannabinoid signaling by inhibiting the breakdown and transport of the endocannabinoid, anandamide (AEA).
6. CBD is legal in all 50 states
Sorry, the Feds still consider CBD illegal and part of the ridiculous Schedule 1 classification of cannabis. While you do not have to worry about state authorities coming after you in some states, the Feds remain the Boogey Man.